DIHYDROTACHYSTEROL (dye-hye-droe-tak-iss'ter-ole) DHT, DHT Intensol, Hytakerol Classifications: vitamin d; regulator, serum calcium Pregnancy Category: A |
0.125 mg, 0.2 mg, 0.4 mg tablets; 0.2 mg/mL oral solution; 0.125 mg capsules
Oil-soluble reduction product of ergocalciferol (vitamin D2) with pharmacologic actions similar to those of both ergocalciferol and parathyroid hormone. In comparison with ergocalciferol, dihydrotachysterol promotes less intestinal absorption of calcium but almost equal phosphate diuresis.
Acts like parathyroid hormone in ability to raise serum calcium concentrations rapidly; also reported to increase intestinal absorption of sodium, potassium, and magnesium.
Hypocalcemia associated with hypoparathyroidism, both postoperative and idiopathic, and in pseudohypoparathyroidism. Also for prophylaxis of hypocalcemic tetany following thyroid surgery.
Vitamin D-resistant rickets (familial hypophosphatemia), osteoporosis, and renal osteodystrophy.
Sensitivity to vitamin D; hypercalcemia and hypocalcemia associated with renal insufficiency and hyperphosphatemia; renal stones, hypervitaminosis D. Safe use during pregnancy (category A), lactation, or in children in amounts exceeding RDA is not established.
Hypoparathyroidism, Pseudohypoparathyroidism Adult: PO 0.752.5 mg/d for several days, then 0.21 mg/d (may need 1.5 mg/d) Child: PO 15 mg/d for 4 d then 0.51.5 mg/d Neonate: PO 0.050.1 mg/d Thyroidectomy-induced Hypocalcemia Adult: PO 0.25 mg/d Renal Osteodystrophy Adult: PO 0.10.6 mg/d Child: PO 0.10.5 mg/d |
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