|FOLIC ACID (VITAMIN B9, PTEROYLGLUTAMIC ACID)
Apo-Folic , Folacin, Folvite, Novofolacid
Classifications: vitamin b9
Pregnancy Category: A
0.4 mg, 0.8 mg, 1 mg tablets; 5 mg/mL injection
Vitamin B complex essential for nucleoprotein synthesis and maintenance of normal erythropoiesis. Acts against folic acid deficiency that impairs thymidylate synthesis and results in production of defective DNA that leads to megaloblast formation and arrest of bone marrow maturation.
Stimulates production of RBCs, WBCs, and platelets in patients with megaloblastic anemias. Include improved symptoms of glossitis, diarrhea, constipation, weight loss, irritability, fatigue, restless legs, diffuse muscular pain, insomnia, forgetfulness, mental depression, pallor.
Folate deficiency, macrocytic anemia, and megaloblastic anemias associated with malabsorption syndromes, alcoholism, primary liver disease, inadequate dietary intake, pregnancy, infancy, and childhood.
Folic acidalone for pernicious anemia or other vitamin B12 deficiency states; normocytic, refractory, aplastic, or undiagnosed anemia.
Pregnancy (category A), lactation.
Adult: PO/IM/SC/IV 1 mg/d
Child: PO/IM/SC/IV 1 mg/d
Adult: PO/IM/SC/IV 0.4 mg/d
Child: PO/IM/SC/IV <4 y, 0.3 mg/d; >4 y, 0.4 mg/d
Infant: PO/IM/SC/IV 0.1 mg/d
PREPARE: Direct/Continuous: Given undiluted.
ADMINISTER: Direct/Continuous: Give over 3060 sec. May also add to a continuous infusion.
INCOMPATIBILITIES Solution/additive: Doxapram.
Falsely low serum folate levels may occur with Lactobacillus casei assay in patients receiving antibiotics such as tetracyclines.
Assessment & Drug Effects
Patient & Family Education